Periop Leader Week
September 30, 2025

What periop nurses should preoperatively know about GLP-1, oral GLP-1 drugs

With the explosion of GLP-1–based therapies for type 2 diabetes and weight loss, perioperative nursing teams, especially in the preoperative and postanesthesia care areas, need to be fluent in recognizing these medications. Some patients may arrive on these agents—or even novel oral GLP-1s—and the physiologic effects, especially delayed gastric emptying, can influence anesthesia risk, aspiration precautions, and timing decisions.

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