Editor's Note An experimental compound developed at Duke University School of Medicine provides strong pain relief without the side effects or addiction potential of opioids, according to a May 19 announcement from the university. Known as SBI-810, the drug targets a specific receptor in the nervous system and uses a…
Editor's Note Research shows patients undergoing procedural sedation for endoscopic procedures experience significant and often undetected heat loss comparable to that seen during general anesthesia despite widespread assumptions that sedation preserves thermoregulation. Findings were published May 27 in The Journal of PeriAnesthesia Nursing. Conducted at a tertiary hospital in…
Editor's Note Blocking stress-induced prolactin may significantly reduce postoperative pain in women and curb the need for opioids, according to a study led by University of Arizona Health Sciences. News-Medical.Net summarized the findings May 20. Published in Proceedings of the National Academy of Sciences, the research suggests a path toward…
Editor's Note Helping patients taper opioids preoperatively before deploying multimodal care strategies can help prevent instances of patients already with prescriptions going home with even higher doses. That’s the main takeaway from an April 22 MedCentral interview with Marie N. Hanna, MD, division chief for regional anesthesia and acute pain…
Editor's Note Using powerful synthetic opioids remifentanil and sufentanil during surgery increases risk of patients suffering during recovery, according to a study in the journal Regional Anesthesia & Pain Medicine. HealthDay reported the news February 27. According to the article, researchers analyzed data from 971 patients who underwent surgery—37% orthopedic…
Editor's Note The FDA has approved Journavx (suzetrigine), a first-in-class non-opioid analgesic, for the treatment of moderate to severe acute pain in adults. According to the agency’s January 30 announcement, the drug targets sodium channels in the peripheral nervous system to block pain signals before they reach the brain, representing…
Editor's Note Implementing a multimodal analgesia-based enhanced recovery after surgery (ERAS) protocol significantly reduced both intraoperative opioid administration and postoperative opioid prescriptions in cardiac surgery patients, according to a January 5 report in Anesthesiology News. The findings were presented at the 2024 International Anesthesia Research Society meeting by Montefiore-Einstein Center…
Editor's Note Black patients are less likely to receive multimodal analgesia and more likely to be given additional oral opioids compared to white patients, according to research presented at the Anesthesiology 2024 annual meeting. According to an October 20 report on the retrospective study from the American Society of Anesthesiologists,…
Editor's Note Music-based interventions administered preoperatively, intraoperatively, and postoperatively can significantly reduce postoperative opioid use and improve mood in patients undergoing same-day surgeries, according to research published October 15 in the Journal of Clinical Medicine. The single-center, prospective, randomized controlled trial evaluated 75 patients aged 18 to 80 who received…
Editor's Note The first clinical guidance for prescribing opioids to children recommend combining the drugs with nonopioid medications like acetaminophen or ibuprofen rather than as monotherapy, according to a September 30 report in Healio. Released by The American Academy of Pediatrics (AAP), the guidance also specifies that naloxone should also…
